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Research publications

Type of cancer Author Evidence No. of patients Therapy Year Sort ascending
Treatment outcome analysis of chemotherapy combined with modulated electro-hyperthermia compared with chemotherapy alone for recurrent cervical cancer, following irradiation Cervical cancer
  • Sun Young Lee
  • Na Ri Lee
  • Dong Hyu Cho
20 CT+mEHT 2017
The safety and pharmacokinetics of high dose intravenous ascorbic acid synergy with modulated electrohyperthermia in Chinese patients with stage III-IV non-small cell lung cancer Lung
  • Ou J
  • Zhu X
  • Lu Y
  • Zhao C
  • Zhang H
  • Wang X
  • Gui X
  • Wang J
  • Zhang X
  • Zhang T
  • Pang C
Phase I 35 mEHT 2017
Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a 2-centre German cohort trial with systematic comparison Brain
  • Roussakow S.
Retrospective study 168 CT+mEHT 2017
PD-1, PD-L1 and CTLA-4 in pregnancy-related e and in early-onset breast cancer: A comparative study Breast cancer
  • Ács B
  • Madaras L
  • Tőkés AM
  • Kovács AK
  • Kovács E
Comparative study 42 mEHT 2017
Local modulated electro-hyperthermia in combination with traditional Chinese medicine vs. intraperitoneal chemoinfusion for treatment of peritoneal carcinomatosis with malignant ascites: a phase II randomized trial Malignant ascites
  • Pang CLK
  • Xinting Z
  • Zhen W
  • Junwen O
  • Yimin L
  • Roussakow R
Phase II 260 mEHT 2017
Positive response of a primary leiomyosarcoma of the breast following salvage hyperthermia and pazopanib Leiomyosarcoma of the breast
  • Sun Young Lee
  • Na-Ri Lee
Case report 1 CT+mEHT 2016
Update on phase III randomized clinical trial investigating the effects of the addition of electro-hyperthermia to chemora-diotherapy for cervical cancer patients in South Africa Cervix
  • C Minnaar
  • A Baeyens
  • J Kotzen
Phase III 100 CT+mEHT 2016
Definitive radiotherapy with concurrent oncothermia for stage IIIB non‑small‑cell lung cancer: A case report Lung
  • Seung-Gu Yeo
Case report 1 RT+mEHT 2015
Long-term survival of a breast cancer patient with extensive liver metastases upon immune and virotherapy: a case report Breast cancer
  • Schirrmacher V
  • Stücker W
  • Lulei M
  • Bihari AS
  • Sprenger T
Case report 1 SRG+mEHT 2015
The Outcome of the Chemotherapy and Oncothermia for Far Advanced Adenocarcinoma of the Lung: Case reports of four patients Lung
  • Doo Yun Lee
  • Joon Seok Park
  • Hae Chul Jung
  • Eun Seol Byun
  • Seok Jin Haam
  • Sung Soo Lee
Case report 4 CT+mEHT 2015
Results of oncothermia combined with operation, chemotherapy and radiation therapy for primary, recurrent and metastatic sarcoma Sarcoma
  • Tae Sig Jeung
  • Sun Young Ma
  • JiHoon Choi
  • Jeasang Yu
  • Su Yong Lee
  • Sangwook Lim
13 SRG+CT+mEHT 2015
Current Status of Oncothermia Therapy for Lung Cancer Lung
  • Andras Szasz, Ph.D.
CT+RT+mEHT 2014
Sorafenib and locoregional deep electro‑hyperthermia in advanced hepatocellular carcinoma: A phase II study Gastrointestinal
  • Gennaro Gadaleta-Caldarola
  • Stefania Infusino
  • Ida Galise
  • Girolamo Ranier
  • Gianluca Vinciarelli
  • Vito Fazio
  • Rosa Divella
  • Antonella Daniele
  • Gianfranco Filippelli
Phase II 21 CT+mEHT 2014
Long‑term remission of prostate cancer with extensive bone metastases upon immuno‑ and virotherapy: A case report Prostate
  • Volker Schirrmacher
  • Akos-Sigmund Bihari
  • Wilfried Stücker
  • Tobias Sprenger
Case report 1 SRG+CT+mEHT 2014
The results of combination of ifosfamid and locoregional hyperthermia (EHY 2000) in patients with advanced abdominal soft-tissue sarcoma after relapse of first line chemotherapy Sarcoma
  • Volovat C
  • Volovat SR
  • Scripcaru V
  • Miron L
  • Lupascu C
24 CT+mEHT 2014
Second-line chemotherapy with gemcitabine and oxaliplatin in combination with loco-regional hyperthermia (EHY-2000) in patients with refrctory metastatic pancreatic cancer - preliminary results of a prospective trial Pancreas
  • Volovat C
  • Volovat SR
  • Scripcaru V
  • Miron L
Clinical study 26 CT+mEHT 2014
Oncothermia with chemotherapy in the patients with Small Cell Lung Cancer Lung
  • Doo Yun Lee
  • Seok Jin Haam
  • Tae Hoon Kim
  • Jae Yoon Lim
  • Eun Jung Kim
  • Na Young Kim
Phase I 31 CT+mEHT 2013
Androtherm application for the Peyronie's Disease Andrology & prostate
  • Ballerini M
  • Baronzio G F
  • Capito G
  • Szasz O
  • Cassutti V
30 mEHT 2013
Oncothermia in HIV positive and negative locally advanced cervical cancer patients in South Africa Cervix
  • Carrie Strauss
  • Jeffrey Kotzen
  • Ans Baeyens
  • Irma Maré
Phase III 236 CT+RT+mEHT 2013
Treatment of advanced cervical cancer with complex chemoradio – hyperthermia Cervix
  • Lajos Pesti
  • Zsófia Dankovics
  • Péter Lorencz
  • András Csejtei
Retrospective study 72 CT+mEHT 2013
Successful Treatment of Advanced Ovarian Cancer with Thermochemotherapy and Adjuvant Immune Therapy Ovarian
  • R. Kleef
  • S. Kekic
  • N. Ludwig
Case report 1 CT+mEHT 2012
Successful Treatment of Solitary Bone Metastasis of Non-Small Cell Lung Cancer with Bevacizumab and Hyperthermia Bone
  • Gábor Rubovszky
  • Tünde Nagy
  • Mária Gődény
  • András Szász
  • István Láng
Case report 1 CT+mEHT 2011
Für und Wider des Prostata-Karzinom-Screenings Andrology & prostate
  • Douwes FR
2011
Neue Studie heizt Diskussion über den Wert von PSA-Tests an Andrology & prostate
  • Douwes FR
2011
Adjuvante Radiotherapie: Welcher Patient mit Prostatakarzinom profitiert? Andrology & prostate
  • Douwes FR
2011
Transcranial electro-hyperthermia combined with alkylating chemotherapy in patients with relapsed high-grade gliomas: phase I clinical results Glioma
  • Wismeth C
  • Dudel C
  • Pascher C
  • Ramm P
  • Pietsch T
  • Hirschmann
  • Reinert C
  • Proescholdt M
  • Rümmele P
  • Schuierer G
  • Bogdahn U
  • Hau P
Phase I 15 CT+mEHT 2009
Clinical study for advanced non-small-cell lung-cancer treated by oncothermia Lung
  • Dani A
  • Varkonyi A
  • Magyar T
  • Szasz A
Open-label study 258 CT+RT+mEHT 2009
Clinical study for advanced pancreas cancer treated by oncothermia Pancreas
  • Dani A
  • Varkonyi A
  • Magyar T
  • Szasz A
Clinical study 99 CT+RT+mEHT 2008
Prostatakarzinom: Neue Aspekte für Diagnostik und Therapie Andrology & prostate
  • Douwes FR
2008
Sanfte Hilfen für die Prostata Andrology & prostate
  • Douwes FR
2008
Prospective phase II trial for recurrent high-grade malignant gliomas with capacitive coupled low radiofrequency (LRF) deep hyperthermia Brain
  • Hager ED
  • Sahinbas H
  • Groenemeyer DH
  • Migeod F
Phase II 179 CT+RT+mEHT 2008
Intra-arterial and Systemic Chemotherapy plus External Hyperthermia in Unresectable Biliary Cancer Gastrointestinal
  • A. Mambrini
  • A. Del Freo
  • P. Pacetti
  • M. Orlandi
  • T. Torri
  • G. Fiorentini
  • M. Cantore
16 CT+mEHT 2007
Retrospective clinical study of adjuvant electro-hyperthermia treatment for advanced brain-gliomas Brain
  • Sahinbas H
  • Groenemeyer DHW
  • Boecher E
  • Szasz A
Retrospective study 140 mEHT 2007
Deep electro-hyperthermia (EHY) with or without thermo-active agents in patients with advanced hepatic cell carcinoma: phase II study Liver
  • Ferrari VD
  • De Ponti S
  • Valcamonico F
  • Amoroso V
  • Grisanti S
  • Rangoni G
  • Marpicati P
  • Vassalli L
  • Simoncini E
  • Marini G
Phase II 22 SRG+CT+mEHT 2007
A Phase II Clinical Study on Relapsed Malignant Gliomas Treated with Electro-hyperthermia Glioma
  • Giammaria Fiorentini
  • Petros Giovanis
  • Susanna Rossi
  • Patrizia Dentico
  • Raffaele Paola
  • Gina Turrisi
  • Paolo Bernardeschi
Phase II 12 CT+RT+mEHT 2006
Behandlung des fortgeschrittenen Pankreaskarzinoms mit regionaler Hyperthermie und einer Zytostase mit Mitomycin- C und 5-Fluorouracil/ Folinsäure Pancreas
  • Douwes F
  • Migeod F
  • Grote C
30 CT+mEHT 2006
Thermo-chemotherapy of the advanced pancreas carcinoma Pancreas
  • Douwes FR
18 CT+mEHT 2006
Glioblastoma multiforme Grad IV: Regionale Tiefenhyperthermie, Antiangiogenese mit Thalidomid, Hochdosis-Ascorbinsäureinfusionen und komplementäre Therapie Brain
  • Hager ED
  • Birkenmeier J
2006
Hyperthermia in combination with ACNU chemotherapy in the treatment of recurrent glioblastoma Brain
  • Douwes F
  • Douwes O
  • Migeod F
  • Grote C
  • Bogovic J
19 sRG+CT+RT+mEHT 2006
Malignes Melanom Stadium IV: Anwendung von regionaler Tiefenhyperthermie, Tamoxifen, Interferon-α und komplementären Therapien Melanoma
  • Hager ED
  • Birkenmeier J
2006
Bestrahlung der Prostata erhöht Rektum-Ca-Risiko Andrology & prostate
  • Douwes FR
2005
Thermo-Chemotherapie des fortgeschrittenen Pankreaskarzinoms. Ergebnisseeiner klinischen Anwendungsstudie Pancreas
  • Douwes FR
Clinical study 30 CT+mEHT 2004
Rebell gegen den Krebs. Bioogische Intersivtherapie – Neue Hoffnung für Patienten? Andrology & prostate
  • Maar K
2004
Lebermetastasen bei kolorektalen Karzinomen Liver
  • Hager ED
2004
Whole-body hyperthermia in combination with platinum-containing drugs in patients with recurrent ovarian cancer Ovarian
  • Friedrich Douwes
  • Juri Bogovic
  • Ortrun Douwes
  • Friedrich Migeod
  • Christoph Grote
21 CT+mEHT 2003
Malignus és belignus prosztatadaganatok hyperthermiája Andrology & prostate
  • Szasz A
252 mEHT 2003
The treatment of patients with high-grade malignant gliomas with RF-hyperthermia Brain
  • Hager ED
  • Dziambor H
  • App EM
  • Popa C
  • Popa O
  • Hertlein M
36 CT+RT+mEHT 2003
Radiofrequency Transurethral Hyperthermia and complete Androgen Blockade. A Nonsurgical Approach to Treating Prostate Cancer Andrology & prostate
  • Douwes FR
  • Lieberman S
184 mEHT 2002
Posttreatment Histology and Microcirculation Status of Osteogenic Sarcoma after a Neoadjuvant Chemo- and Radiotherapy in Combination with Local Electromagnetic Hyperthermia Bone
  • Bogovic J
  • Douwes F
  • Muravjov G
  • Istomin J
Retrospective study 62 CT+RT+mEHT 2001
Diagnostik hyperthermia in early stage prostate cancer Andrology & prostate
  • Douwes FR
2001
Transurethral hyperthermia in early stage prostate cancer Andrology & prostate
  • Douwes FR
34 mEHT 2001
Deep hyperthermia with radiofrequencies in patients with liver metastases from colorectal cancer Gastrointestinal
  • Hager ED
  • Dziambor H
  • Höhmann D
  • Gallenbeck D
  • Stephan M
  • Popa C.
Clinical study 80 CT+mEHT 1999
Hoffnung bei Prostata-Beschwerden. Die neue Therapie ohne Messer Andrology & prostate
  • Douwes F
  • Sillner L
  • Köhnlechner M
1999
Complex therapy of the not in sano respectable carcinoma of the pancreas – a pilot study Pancreas
  • Hager ED
  • Süsse B
  • Popa C
  • Schritttwieser G
  • Heise A
  • Kleef R
1994