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04/16/2021 - 07:35 | Science

Clinical study of modulated electro‑hyperthermia for advanced metastatic breast cancer

Takuya Nagata, Masahiko Kanamori, Shinichi Sekine, Mie Arai, Makoto Moriyama, Tsutomu Fujii

The aim of the present study was to report the outcomes of mEHT in the treatment of advanced breast cancer. mEHT was used to treat in 10 patients with advanced metastatic breast cancer and recurrent disease, who were considered incurable by standard therapy protocols. Of the 10 patients, partial response was achieved in 3, disease stability in 3, and progressive disease in 4; however, their quality of life was improved based on their subjective reports. No adverse effects were observed in any of the 10 patients. The present study demonstrated the feasibility of mEHT as a possible therapy for advanced breast cancer cases when standard therapies fail. Moreover, mEHT had no side effects and may be combined with various treatments for long‑term therapy.