Oncothermia treatment induced immunogenic cancer cell death
Andocs G
Meggyeshazi N
Okamoto Y
Balogh L
Kovago Cs
Szasz O
Page 28-37
“There are increasing evidence that certain type of anticancer therapeutical methods can induce a very special form of programmed cell death, trigger an immune response against the tumor, so in recent years a new concept of immunogenic cell death (ICD) has emerged [1]. Apoptotic cell death has a vital importance in this process [2], [3], [4]. The immunogenic characteristics of ICD are mainly mediated by damage-associated molecular patterns (DAMPs) [5], [6]. One of the most important key molecules amongs many others are the heat shock proteins (HSPs) [7], [8] and some death receptors [9].
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