Oncothermia treatment induced immunogenic cancer cell death
“There are increasing evidence that certain type of anticancer therapeutical methods can induce a very special form of programmed cell death, trigger an immune response against the tumor, so in recent years a new concept of immunogenic cell death (ICD) has emerged . Apoptotic cell death has a vital importance in this process , , . The immunogenic characteristics of ICD are mainly mediated by damage-associated molecular patterns (DAMPs) , . One of the most important key molecules amongs many others are the heat shock proteins (HSPs) ,  and some death receptors .