We are happy to announce that the Oncothermia Journal Vol. 33
is now available for download!

We recommend the 33rd volume of our Journal to our readers’ attention as essential new results are published and presented in this volume.

The articles cover topics such as the role of resonances in modulated electro-hyperthermia for targeting malignant cells, the complementary use of mEHT with radiotherapies, overcoming heat resistance in hyperthermia treatment, the advantages of mEHT in cervical cancer, and also a commentary provides valuable insights on hyperthermia.

We hope you will enjoy reading these articles and be able to use the provided information in your medical practice!

May is an important month for raising awareness about some types of cancer that affect millions of people around the world. It’s Brain Cancer, and Melanoma & Skin Cancer Awareness Month as these diseases affect countless individuals every year.

For this specific month we’ve collected some informative publications and studies as well, especially on the topic of applying the treatment of mEHT on glioblastomas:

Szasz AM, Arrojo Alvarez EE, Fiorentini G, Herold M, Herold Z, Sarti D, Dank M. (2023)
Meta-analysis of modulated electro-hyperthermia and tumor treating fields in the treatment of glioblastomas
Cancers, 15, 880

Solodkiy VA, Panshin GA, Izmailov TR, Shevchenko TA. (2021)
The first experience of application of remote radiotherapy in combination with hyperthermia (oncothermia) in the treatment of patients with primary gliomas of the brain of a high degree of malignancy,
ВОПРОСЫ ОНКОЛОГИИ (Problems in Oncology), Vol. 67, Nr. 2.

Van Gool SW, Makalowski j, Fiore S, et.al. (2021)
Randomized controlled immunotherapy clinical trials for GBM challenged
Cancers, 13, 32

Van Gool SW, Makalowski j, Bonner ER, et.al. (2020)
Addition of multimodal immunotherapy to combination treatment strategies for children with DIPG: A single institution experience
Medicines, 7, 29

Fiorentini G, Sarti D, Casadei V, et.al. (2020)
Modulated electro-hyperthermia for the treatment of relapsed brain gliomas, in book Challenges and solutions of oncological hyperthermia
ed. Szasz A., Ch. 6, pp.110-125, Cambridge Scholars

Van Gool SW, Makalowski J, Domogalla MP, et.al. (2020)
Personalised medicine in glioblastoma multiforme, in book Challenges and solutions of oncological hyperthermia, ,
ed. Szasz A., Ch. 7, pp.126-158, Cambridge Scholars

Van Gool S, Makalowski J, Marko M. (2019)
Hyperthermia as part of multimodal immunotherapy for patients with GBM,
Oncothermia Journal 27: 122-137

Fiorentini G, Sarti D, Casadei V (2019)
Modulated electro-hyperthermia for the treatment of relapsed brain tumors
Oncothermia Journal 27: 42- 61

Pontes S, Azevedo F. (2019)
Effectiveness Clinical Case Report mEHT – Results on CA – Esterioneuroblastoma – Brazilian Experience
Oncothermia Journal 27: 76-87

Fiorentini G, Casadei V. (2018)
Modulated Electro-Hyperthermia (mEHT) in Integrative Cancer Treatment for Relapased Malignant Gliobastroma and Astrocytoma: a retrospective multicenter controlled study ,
Oncothermia Journal 24: 464-481

Van Gool SW, Makalowski J, Feyen O, Prix L, Schirrmacher V and Stuecker W. (2018)
The induction of immunogenic cell death (ICD) during maintenance chemotherapy and subsequent multimodal immunotherapy for glioblastoma (GBM)
Austin Oncol Case Rep, 3:1-8

Fiorentini G. (2018)
Oncothermia in brain tumours
Oncothermia Journal 22:151-177

Van Gool SW, Makalowski J, Stuecker W. (2018)
Modulated electrohyperthermia (mEHT) as part of multimodal immunotherapy for brain tumors
Oncothermia Journal 248-269

Prieto C, Linares I. (2018)
Nanoparticles and nanothermia for malignant brain tumors, a suggestion of treatment for further investigations
Reports of Practical Oncology and Radiotherapy, 2018 Sep-Oct;23(5):474-480,

Fiorentini G, Sarti D, Milandri C, et.al. (2018)
Modulated electrohyperthermia in integrative cancer treatment for relapsed malignant glioblastoma and astrocytoma: Retrospective multicenter controlled study
Integrative Cancer Therapies, 1-11,

Roussakow S. (2017)
Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison and effect-to-treatment analysis
BMJ Open, 7:e017387

Roussakow SV. (2017)
Systematic Review of Brain Glioma and Lung Cancer Trials with Modulated Electro-Hyperthermia, with Meta-Analysis and Economic Evaluation (Level II Evidence)
Oncothermia Journal Volume 20: 170-216,

Pastore C, Fioranelli M, Roccia MG. (2017)
Rescue therapy in patient with glioblastoma multiforme combining chemotherapy, hyperthermia, phytotherapy
J Integrative Oncology, 6(4):199

Fiorentini G, Sarti D, Milandri C, et.al. (2017)
Retrospective observational clinical study on relapsed malignant gliomas treated with electro-hyperthermia
Int J Neurooncol and Brain Tumors, 1(1):9-13,

Az Oncotherm csapata kellemes Húsvéti ünnepet kíván Önnek és családjának,
tele új kezdetek ígéretével, a jólét és a bőség áldásaival!

The Mirakle Integrated Health Centre celebrated the opening of its hyperthermia treatment center in Pollachi, India, located at Mahalingapuram Nachimuthu Polytechnic University Campus.

The facility is equipped with the latest Oncotherm device, the EHY-2030 to provide targeted and effective cancer treatment to their patients.

The opening celebration included a presentation ceremony and lectures on the benefits of hyperthermia in cancer therapy, and a guided tour of the facility. The event attracted a lot kind of interest. Not only medical practitioners and healthcare experts from the area but patients were drawn to the ceremony which received considerable media attention, television stations and several journalists were present. The General Manager of Oncotherm, Mr. Balázs Ács, and Medical Director Dr. Marcell Szász also took part and shared their insights and expertise on hyperthermia treatment at this specific event. This first hyperthermia treatment center in Pollachi is an important milestone for the market of Oncotherm devices. By expanding the market to India, the treatment options for cancer patients have increased and the hope for successful outcomes has grown.

The Bionext System Pte. Ltd. led by Dr. Domokos Máthé deserves special acknowledgment for their commitment and efforts in successfully implementing this system at the treatment center. With their expertise and experience in the healthcare industry in India, we believe that this partnership will lead to fruitful opportunities and create a strong foundation for growth in the region.

Watch the presentation ceremony here!

As we enter the month of National Colorectal Cancer Awareness in March, we have collected some informative publications and studies on this topic for our Readers. This disease is a significant health concern worldwide and is one of the leading causes of cancer-related deaths.

Our goal is to make a positive impact in the fight against colorectal cancer as these studies have shown promising results related to the application of oncothermia as a treatment.

Kim S, Lee JH, Cha J, You SH. (2021)
Beneficial effects of modulated electro-hyperthermia during neoadjuvant treatment for locally advanced rectal cancer,
Int J Hyperthermia, 38:1, 144-151.

Ranieri G, Laface C, Laforgia M, et.al. (2020)
Bevacizumab plus FOLFOX-4 combined with deep electro-hyperthermia as first-line therapy in metastatic colon cancer: A pilot study,
Frontiers in Oncology, 10:590707,

Kuo I-M, Lee J-J, Wang Y-S, et.al. (2020)
Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro-hyperthermia,
BMC Cancer, 20:603

Vancsik T. (2020)
Mechanism of modulated electro-hyperthermia induced tumor destruction in C26 colorectal cancer models,
Semmelweis University, Doctoral School of Pathological Sciences, PhD thesis

Vancsik T, Forika G, Balogh A, et.al. (2019)
Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro,
Cancer Medicine, (9):4292-4303,

You SH, Kim S. (2019)
Feasibility of modulated electro-hyperthermia in preoperative treatment for locally-advanced rectal cancer: Early phase 2 clinical results,
Neoplasma, 67(3): 677-683,

Vancsik T, Kovago Cs, Kiss E, et al. (2018)
Modulated electro-hyperthermia induced loco-regional and systemic tumor destruction in colorectal cancer allografts,
J Cancer, 9(1): 41-53.

Vancsik T., Kiss E, Kovago Cs, Meggyeshazi N, Forika G, Krenacs T. (2017)
Inhibition of proliferation, induction of apoptotic cell death and immune response by modulated electro-hyperthermia in C26 colorectal cancer allografts, thermometry,
Oncothermia Journal Volume 20 : 277-292.

Iyikesici MS, Slocum A, Turkmen E, et al. (2016)
Complete response of locally advanced (stage III) rectal cancer to metabolically supported chemoradiotherapy with hyperthermia,
Int J Cancer Res Mech, 2(1).

Andocs G, Meggyeshazi N, Balogh L, et al. (2014)
Upregulation of heat shock proteins and the promotion of damage-associated molecular pattern signals in a colorectal cancer model by modulated electrohyperthermia.
Cell Stress and Chaperones 20(1):37-46.

Hager ED, Dziambor H, Höhmann D, et al. (1999)
Deep hyperthermia with radiofrequencies in patients with liver metastases from colorectal cancer.
Anticancer Res 19(4C):3403–3408.

We learned with deep sorrow that Professor Herzog had passed away. He was a renowned, respected, excellent doctor, the chief physician of his clinic. His clinical activity and therapies were highly successful, surrounded by the love of patients. The many patients whose lives he extended think of him with great affection. Colleagues often approached him for advice and consultation. His University lectures and presentations at various conferences had high popularity. His death is a significant loss to his loved ones, friends, and the medical community.

Although he is no longer with us, his strong influence on oncology, his humanity, and his ethical strengths is exemplary for all of us, and his teaching lives with us. We do not forget him. Rest in peace.

Oncotherm Group

Dear Partners,

As this special year comes to an end, we would like to express our sincerest appreciation for all the trust, interest, time, and support you gave to our company. We hope that this year has been just as memorable for you, your colleagues, and your loved ones.
We hope that the next year brings health and happiness to you and your entire family.

We wish you a Merry Christmas and a Happy New Year!

Oncotherm Group

With deep sorrow, we learn that our cooperative partner, colleague, and friend for many of us, Dr. Friedrich Douwes, has passed away.

He was a great doctor with ideas, innovations, and substantial international experience. For him the patient as a person was important. He never treated only the tumour, he considered the tumorous patient as a whole in his approach. He was a pioneer of integrative medicine, successfully treating not only his oncological patients but many comorbidities and other presently less curable diseases, like Lyme disease. His dynamism, intensive, tireless work, and bright intuitions were exemplary for us. We will preserve his memory.

May he rest in peace.

This Monday, Balázs Ács, Managing Director of Oncotherm Kft. represented our company at the Hungarian-Uzbek Business Forum in Budapest. The purpose of the event was to encourage the business representatives of the two countries to establish new economic relations and business cooperation. A high-ranking diplomatic and business delegation from Uzbekistan was present and we had the opportunity to introduce our company. They were really interested in our technology and also invited us to Uzbekistan on the 21st of October where further negotiations will take place about future possibilities.

We are grateful for this opportunity, and we hope that this event marks the beginning of fruitful cooperation in order to strengthen the bilateral relationship between the two countries!

We are happy to announce that the Oncothermia Journal Volume 32
is now available for download!

Oncotherm considers it very important to inform those who are interested in the latest results of hyperthermia and the trends in the emerging field of oncology. The articles of this volume partly cover presentations of clinicians using hyperthermia and indicate impressive results in the 39th Conference of International Clinical Hyperthermia Society (ICHS).

Our goal is to provide relevant and up-to-date information for your clinical practices. We hope that this volume is beneficial to your daily treatment decisions with its valuable observations.

Please enjoy the latest 32nd volume of the Oncothermia Journal!